POST-TRANSLATIONAL MODIFICATIONS OF PRC2: SIGNALS DIRECTING ITS ACTIVITY

Abstract Polycomb repressive complex 2 (PRC2) is a chromatin-modifying enzyme WOMENS SOFTGOODS that catalyses the methylation of histone H3 at lysine 27 (H3K27me1/2/3).This complex maintains gene transcriptional repression and plays an essential role in the maintenance of cellular identity as well as normal organismal development.The activity of PR

Behavioral, biological and social sequelae that lead to drug addiction differ between men and women.Our efforts to understand addiction on a mechanistic level must include studies in both males and females.Stress, anxiety, and depression are tightly linked to addiction, and whether they precede or result from compulsive drug use depends on many fac